Giving a different AV probably means nothing, the odds that JJ2 uses the same memory addresses each time is highly unlikely.

If sound's the issue, then I don't see what the problem is with just playing with -nosound is. It's not as if JJ2 has any memorable or even very interesting sound effects or music.

Other than that, I'm tempted to say it's your processor or to run it in compatibility mode, but both of those are probably as far from true as possible.