There is a fine line between revolutionary and gimmicky. It often varies from person to person, too. Personally, I find it has a lot to do with how much of something is original. I think the Shakespeare manga has no potential, and will simply come across as a needless, gimmicky modification to an existing work (like, "look, it's Shakespear. Only IN JAPANESE").
The comic in a fictional language could work, but only if it's executed well. Frankly, it's not the kind of thing I'd start with. It takes a LOT of both artistic and writing skill to be able to tell a story without words. The writing skill is important even sans text, as doing something original won't automatically make it good - you'll still be expected to use foreshadowing, symbolism, character development, emphasis, and so on, only visually rather than textually.