I agree (hey, I may be a noob on these forums, but in real life..) with the above. I have been using Blender ever since 2.45, so I'm still relatively new, but come on now, Blender would only make tiling more difficult. You'd have to set up all the colors and cut everything out externally and, point is, things come out really rough. Right now, I am working on a tileset using Gimp, it's actually coming out pretty nice, probably not as convenient as Photo though.