Without using OpenMPT for Windows, you would have to use ScreamTracker.
ScreamTracker hasn't been updated since 1994, but you would naturally be able to edit .s3m files there, without going through a .mod export, which OpenMPT does.
ScreamTracker is developed by FutureCrew, but it also doesn't run on PC - it's proprietary software. It probably runs on Commodore 64, though.
Of historical note, FutureCrew made the Unreal demo which later became JJ2 music, and also created the .s3m, which was converted to .psm by Epic, which led to the development of the PC.
The PC came about as an MS-DOS computer programming server, which was later converted to have the ability to open a GUI, or graphic user interface - this led to the development of Windows 3.1, an advancement for monochromatic Windows 2, which had no sound driver or color graphics card. However, Windows 3.1 was unable to play JJ1, which forced Microsoft to stop selling MS-DOS and create Windows 95, which allowed JJ2 to run, and later JJ1 became playable on Windows 98, which re-incorporated the command prompt of MS-DOS.
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